Author

Isabelle Johnson

Memorial Sloan Kettering Cancer CenterORCID 0009-0006-0357-6832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aditi ChandraiD· 1 shared Ali NajiiD· 1 shared Amy M. CookeiD· 1 shared Chengyang LiuiD· 1 shared Darshan D. Mehta· 1 shared Golnaz VahediiD· 1 shared Justin AdleriD· 1 shared Klaus H. KaestneriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Aditi ChandraORCID

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2 papers

Recent·Most cited

An inducible tethered function assay reveals differential regulatory effects for the RNA-binding protein YBX3 and its domains.

William Skipper, Darshan D. Mehta, Justin Adler, Nathan Rose, Isabelle Johnson, Zachary J. Bressman, Michael D. Sheets, Amy M. Cooke

The paper develops an inducible tethered function assay (iTFA) to analyze the regulatory effects of RNA-binding protein domains, specifically demonstrating its application to YBX3.

bioRxiv · Jul 2, 2025 · PreprintMolecular Biology

Aberrant TNF signaling in pancreatic lymph nodes of patients with Type 1 Diabetes

Maryam Abedi, Priyadarshini Rai, Yeqiao Zhou, Chengyang Liu, Isabelle Johnson, Aditi Chandra, Maria Fasolino, Susan Y Rostami, Klaus H. Kaestner, Ali Naji, Robert B. Faryabi, Golnaz Vahedi

This study identifies heightened TNF pathway activity and chromatin remodeling in pancreatic lymph node CD4+ T cells from T1D patients, supporting the use of TNF inhibitors in clinical trials.

bioRxiv · May 31, 2024 · PreprintImmunology