Author

Isaac Toleman

University of CambridgeORCID 0009-0006-1121-3863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Grant Duncan StewartiD· 1 shared Greta BaltušytėiD· 1 shared James O. JonesiD· 1 shared Kourosh Saeb‐ParsyiD· 1 shared Namshik HaniD· 1 shared Sarah Joanne WelshiD· 1 shared Thomas J. MitchelliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Grant Duncan StewartORCID

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1 paper

Recent·Most cited

BioinformaticsCommunications ChemistryPeer-reviewedMay 6, 2026

A network medicine framework for multi-modal data integration in therapeutic target discovery

Greta Baltušytė, Isaac Toleman, James O. Jones…·Namshik Han

This paper presents a network medicine framework integrating multi-modal data to identify therapeutic targets in clear cell renal cell carcinoma, recovering established targets and predicting five candidates, with ENO2 inhibition showing the strongest anti-tumour effect.

1 citation

humanscRNA-seq

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