Kai Yuan

Genome-wide association study of grain iron and zinc concentrations in a diverse CIMMYT wheat panel across contrasting moisture environments

This study identifies genetic loci associated with grain iron and zinc concentrations in wheat under different moisture conditions using genome-wide association analysis.

ArchaicSeeker 3.0: A deep-learning framework for scalable, haplotype-resolved inference of archaic introgression

ArchaicSeeker 3.0 detects archaic introgression using deep learning, outperforming existing methods in precision, recall, and F1 score across diverse genomic contexts and population sizes.

Genomic insights into substance use and disinhibitory disorders

This study identifies 1,294 genomic regions and 961 effector genes associated with externalizing disorders, revealing neural mechanisms and polygenic predictors of variance in these conditions.

AdmixSim: A Forward-Time Simulator for Various and Complex Scenarios of Population Admixture

AdmixSim generates synthetic admixture data under complex scenarios, enabling accurate simulation of population admixture dynamics and facilitating comparative studies.

Inference of multiple-wave population admixture by modeling decay of linkage disequilibrium with multiple exponential functions

This paper introduces MALDmef, a method for inferring multiple-wave admixture by modeling LD decay with multiple exponential functions, showing improved accuracy over existing methods in simulated and real data.

Length Distribution of Ancestral Tracks under a General Admixture Model and Its Applications in Population History Inference

This paper derives the length distribution of ancestral tracks under a general admixture model and applies it to infer population histories with high accuracy.