Author

Thomas Ku

University of Southern CaliforniaORCID 0009-0006-1647-2979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Ao Xu· 1 shared Emily Nguyen· 1 shared Vsevolod KatritchiD· 1 shared Wenjin LiuiD· 1 shared Woojin LeeiD· 1 shared Yongchan HongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Ao Xu

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintSep 4, 2026

When DL-Based Prescreening Meets Synthon-Based Docking: Target-Adapting PharmacoNet via MEL-Steered Correction

Wenjin Liu, Yongchan Hong, Thomas Ku…·Vsevolod Katritch

The paper adapts a general pharmacophore prescreening method to specific targets using fragment-docking data from the V-SYNTHES pipeline, improving its performance without additional data or retraining.

DOI 10.64898/2026.09.02.748684

protein structurestatistical model

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