Joachim Greiner

This study compares the defibrillation efficacy of different channelrhodopsins in human cardiac tissue using simulations, finding that ion selectivity affects arrhythmia termination mechanisms and success.

The paper quantifies TATS ultrastructural features across eight mammalian species and finds correlations between TATS density, cardiomyocyte size, and physiological parameters like heart rate and lifespan.

This study shows that disturbed repolarisation-relaxation coupling during acute ischaemia increases systolic mechano-arrhythmogenesis, which can be mitigated by restoring coupling or targeting calcium, TRPA1, or ROS.

This study uses single-cell RNA-sequencing and spatial transcriptomics to analyze the spatio-temporal dynamics of the fibrotic niche in cardiac repair after ventricular injury in adult mice, identifying key cell interactions and regulatory mechanisms.

This study compares stretch-activated channel activity in bone marrow-derived and cardiac tissue-resident macrophages, finding that Piezo1 activity is absent in the latter.

This study shows that TRPA1 activation and disrupted repolarisation-relaxation coupling during systole contribute to mechano-arrhythmogenesis in ischaemic conditions.

This study examines the structure and dynamics of cardiac fibroblast nanotubes in human atrial tissue and cell lines, showing their role in intercellular communication and ECM interaction.