Author

Karolína Trachtová

Central European Institute of Technology – Masaryk UniversityORCID 0009-0006-1835-8862Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Lukas KenneriD· 3 shared Martina Tomberger· 3 shared Boris TichýiD· 2 shared Christina SternbergiD· 2 shared Desiree Lindner· 2 shared Felix SternbergiD· 2 shared Gerda EggeriD· 2 shared Heidi Anne NeubaueriD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Lukas KennerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 13, 2026

Amygdala metabolic activity on FDG PET is associated with survival, response to immune checkpoint inhibition, and tumor immune signaling in non-small cell lung cancer

Barbara Katharina Geist, Chrysoula Vraka, Clara T.S. Mertel…·Marcus Hacker

DOI 10.64898/2026.09.10.750685

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular CancerPeer-reviewedOct 31, 2024

Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

Christina Sternberg, Martin Raigel, Tanja Limberger…·Lukas Kenner

This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.

17 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular CancerPeer-reviewedMay 29, 2024

JUN mediates senescence and immune cell recruitment to prevent prostate cancer progression

Torben Redmer, Martin Raigel, Christina Sternberg…·Lukas Kenner

This study shows JUN suppresses prostate cancer progression by inducing senescence and immune cell recruitment, with JUN depletion accelerating tumor growth.

39 citationstop 3%

mousebulk RNA-seq

𝕏 PostBluesky