Xiaojun Sun

CellMethMarker provides a database of DNA methylation markers specific to human cell and tissue types, improving deconvolution accuracy in single-cell methylomes.

OTTER improves bisulfite deconvolution in tumor xenograft sequencing by restoring recall to 52%-54% while preserving transcriptomic accuracy.

ctDNA-BERT scores individual bisulfite reads for cell-free DNA methylation analysis, achieving high accuracy in cancer staging without cohort-specific retraining.