Author
Chinese Academy of SciencesORCID 0000-0002-1439-7606Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Xiaojun Sun, Yujie Peng, Yingyu Yi…·Fan Zhang
CellMethMarker provides a database of DNA methylation markers specific to human cell and tissue types, improving deconvolution accuracy in single-cell methylomes.
Yanhua Zheng, Xin Liu, Yingyu Yi…·Fan Zhang
OTTER improves bisulfite deconvolution in tumor xenograft sequencing by restoring recall to 52%-54% while preserving transcriptomic accuracy.
Xuchao Zhang, Xiaojun Sun, Rui Wang…·Fan Zhang
ctDNA-BERT scores individual bisulfite reads for cell-free DNA methylation analysis, achieving high accuracy in cancer staging without cohort-specific retraining.
David Gokhman, Malka Nissim‐Rafinia, Lily Agranat-Tamir…·Liran Carmel
The paper identifies extensive methylation changes in genes related to facial and vocal anatomy in modern humans compared to ancient humans and chimpanzees.