Cell BiologyProceedings of the National Academy of SciencesPeer-reviewed
Global Profiling of N-terminal Cysteine-Dependent Degradation Mechanisms
Aizat Bekturova, Yaara Makaros, Shahar Ben-David, Itay Koren
The paper identifies the Cys-Arg/N-degron pathway as a major regulator of the cysteine-commencing proteome, revealing its role in hypoxia-induced metabolic adaptation and cell survival.
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