Itay Koren

This study identifies KLHL9 as a host factor that interacts with KSHV vBcl-2 and supports lytic replication by facilitating its mitochondrial localization and function.

This study identifies RPL22L1 as a BAG6-RNF115 substrate whose degradation is regulated by its assembly state into the ribosome, revealing a mechanism linking protein quality control to ribosome biogenesis.

The paper identifies the Cys-Arg/N-degron pathway as a major regulator of the cysteine-commencing proteome, revealing its role in hypoxia-induced metabolic adaptation and cell survival.