Author

Hanwen Xu

University of WashingtonORCID 0009-0006-5227-6836Unclaimed ORCID profile · follow to get notified of new preprints

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Hanwen Xu1 paper · University of Washington

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:contrastive learning· 2 Approach:deep learning· 2 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

Sheng WangiD· 2 shared Addie WoicikiD· 1 shared Anupama JhaiD· 1 shared Ghulam MurtazaiD· 1 shared Hoifung PooniD· 1 shared Jiacheng LiniD· 1 shared Jianzhu MaiD· 1 shared Junwei YangiD· 1 shared

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2025-2025 · peak 2/yr

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10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Sheng WangORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 18, 2025

Evo2HiC: a multimodal foundation model for integrative analysis of genome sequence and architecture

Tangqi Fang, Yongkang Li, Zhiping Xiao…·Sheng Wang

Evo2HiC improves prediction of 3D genome architecture and epigenomic signals by integrating DNA sequences and Hi-C data, achieving better accuracy and computational efficiency.

DOI 10.1101/2025.11.18.689171

multiple speciesHi-C

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Molecular BiologyCell GenomicsPeer-reviewedJun 3, 2025

Pisces: A multi-modal data augmentation approach for drug combination synergy prediction

Hanwen Xu, Jiacheng Lin, Addie Woicik…·Sheng Wang

Pisces enhances drug combination synergy prediction by generating 64 augmented views per drug pair, achieving state-of-the-art results across multiple prediction tasks.

7 citations

humanproteomics

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