Author

Zhiping Xiao

University of WashingtonORCID 0000-0002-8583-4789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:contrastive learning· 2 Approach:deep learning· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sheng WangiD· 3 shared Junwei YangiD· 2 shared Ming ZhangiD· 2 shared Anupama JhaiD· 1 shared Bin FengiD· 1 shared Ghulam MurtazaiD· 1 shared Gongbo Sun· 1 shared Han Zhang· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioinformatics

Sheng WangORCID

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3 papers

Recent·Most cited

A multi-agent system for spine MRI report generation from multi-sequence imaging

Zhiping Xiao, Junwei Yang, Gongbo Sun, Han Zhang, Hanwen Xu, Yi Yao, Zachary D. Miller, William E. King, Mohammed M Kanani, Jalal B. Andre, Sammy Chu, Ming Zhang, Paul E. Kinahan, Nathan M. Cross, Sheng Wang

SpineAgent generates spine MRI reports by integrating multi-sequence data using a multi-agent framework, achieving state-of-the-art performance and strong generalizability.

bioRxiv · Jun 11, 2026 · PreprintBioinformatics

Evo2HiC: a multimodal foundation model for integrative analysis of genome sequence and architecture

Tangqi Fang, Yongkang Li, Zhiping Xiao, Shengqi Hang, Ghulam Murtaza, Junwei Yang, Hanwen Xu, Anupama Jha, William Stafford Noble, Sheng Wang

Evo2HiC improves prediction of 3D genome architecture and epigenomic signals by integrating DNA sequences and Hi-C data, achieving better accuracy and computational efficiency.

bioRxiv · Nov 18, 2025 · PreprintBioinformatics

A foundation model for bioactivity prediction using pairwise meta-learning

Bin Feng, Zequn Liu, Nanlan Huang, Zhiping Xiao, Haomiao Zhang, Srbuhi Mirzoyan, Hanwen Xu, Jiaran Hao, Yinghui Xu, Ming Zhang, Sheng Wang

ActFound is a foundation model for bioactivity prediction trained on 2.3 million compounds and 50,869 assays, showing strong generalization and performance comparable to FEP+(OPLS4).

bioRxiv · Oct 30, 2023 · PreprintBioinformatics