Author

Swayamshree Senapati

Indian Institute of Technology BhubaneswarORCID 0009-0006-6114-259XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Ajeet K. SharmaiD· 1 shared Dimple NotaniiD· 1 shared Hemant Kumar· 1 shared Hemant KumariD· 1 shared Inayat Ullah IrshadiD· 1 shared Jyothi S. PrabhuiD· 1 shared Mohit Kumar JollyiD· 1 shared Sarthak SahooiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Ajeet K. SharmaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 13, 2026

Endocrine therapy-specific lineage and partial epithelial-mesenchymal reprogramming defines divergent resistant cell-states in ER+ breast cancer

Sarthak Sahoo, Sejal Khanna, Swayamshree Senapati…·Mohit Kumar Jolly

This study identifies drug-specific resistance mechanisms in ER+ breast cancer by analyzing multi-omic data, revealing distinct transcriptional and chromatin states associated with SERM, SERD, and ESR1 mutant resistance.

DOI 10.64898/2026.05.11.724242

humanbulk RNA-seq

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Biophysicsnpj Systems Biology and ApplicationsPeer-reviewedApr 15, 2025

Polymer Model Unveils Quantitative Association of Chromatin Conformation and Gene Regulation

Swayamshree Senapati, Inayat Ullah Irshad, Ajeet K. Sharma, Hemant Kumar

The paper introduces a computational framework linking chromatin structure to gene regulation using polymer models and Hi-C data, showing how CTCF deletion affects gene expression in limb development.

8 citations

humanHi-C

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