Aaron M. Holleman

The paper identifies rare variants in CFHR5 associated with reduced risk of AMD and increased retinal thickness, suggesting CFHR5 as a therapeutic target.

The paper introduces a kernel method to dissect genetic signals in high-dimensional phenotypes, showing it controls type I error and identifies direct effects in GWAS data.

This paper introduces a method to improve genetic association testing for psychiatric symptoms by analyzing multivariate questionnaire data instead of collapsing it into a single score, showing increased power and efficiency.