Mendell Rimer

This study shows that upregulation of β2* nAChRs in SNc DA neurons protects female parkinsonian mice from neurodegeneration without ligand activation.

This study shows that mitochondrial DNA damage in SNc astrocytes worsens dopaminergic neuron loss in a Parkinson's disease mouse model.

This study shows brain-region-specific differences in astrocytic responses to mitochondrial DNA damage using a novel AAV-based tool in mice.