Zhonghan Deng

CellBinDB provides a large-scale multimodal annotated dataset for cell segmentation and benchmarks seven state-of-the-art methods.

The paper fills a gap in 3D spatial transcriptomics by providing data from E9.5 and E11.5 mouse embryos, enabling detailed analysis of organogenesis with a new open-access database.

The paper updates a software tool to generate single-cell spatial gene expression profiles using cell boundary images from Stereo-seq data, showing improved performance on mouse liver and Arabidopsis seed datasets.