BioengineeringNature CommunicationsPeer-reviewed
Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag
E. H. Brumbaugh-Reed, Yang Gao, Kazuhiro Aoki, Jared E. Toettcher
This paper introduces OptoMBP, a light-controlled method to rapidly and reversibly dissolve biomolecular condensates, demonstrating its application in reversing FUS-CHOP-driven transcriptional changes.
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