Author
Vanderbilt University Medical CenterORCID 0009-0007-0153-5073Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Matthew J. O’Neill, Ayesha Muhammad, Bian Li…·Andrew Michael Glazer
The paper shows that most SCN5A missense loss-of-function variants cause dominant negative effects and are associated with higher Brugada Syndrome risk.
Andrew Michael Glazer, Yuko Wada, Bian Li…·Dan M. Roden
This study reclassifies SCN5A variants using high-throughput patch clamping, finding most variants of uncertain significance are either benign or pathogenic.
Andrew Michael Glazer, Lisa A. Bastarache, Lynn D. Hall…·Dan M. Roden
The paper identifies HFE E168Q as a novel pathogenic variant associated with hereditary hemochromatosis using Phenotype Risk Scores and validates its mechanism through experimental assays.