Simon Murray

EXCON automates CAFE-based gene family expansion and contraction analysis, identifying 358 rapidly evolving families in primates, including DUX gene copy-number turnover.

The paper creates a regulon atlas mapping TF activity across human cell types and uses it to link disease signatures to cell types and TFs, improving disease risk locus analysis.

This study creates a single-cell spatial atlas of the developing human reproductive tract, identifying genes and mechanisms involved in sexual dimorphism and organ development.

This study constructs a multiomic atlas of human early skeletal development using single-nuclei transcriptomics, epigenomics, and spatial transcriptomics to uncover regulatory mechanisms and cell states involved in bone and joint formation.

This study uses single-cell transcriptomics to map the early placental response to three pathogens in first-trimester human placenta, identifying coordinated inflammatory responses and pathogen-specific effects.