Synthetic BiologybioRxivPreprint
Programmable synthetic cytokine receptors polarize macrophages to user-defined functional states
Judith C. Lunger, Lucas E. Sant’Anna, Antonio Salcido-Alcántar…·Kyle G. Daniels
This paper introduces a synthetic cytokine receptor platform that programmably polarizes macrophages to defined functional states, showing enhanced phagocytosis and tumor reduction in mice.
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