BioinformaticsbioRxivPreprint
The topology of transmembrane protein-protein interaction interfaces is encoded in their physicochemical features
Lisa Allmesberger-Riegler, Fabian Frommelt, Brianda L. Santini…·Peter Sykacek
The paper analyzes physicochemical features of transmembrane protein-protein interfaces to determine their topology, finding that amino acid composition and secondary structure are key predictors.
DOI 10.64898/2026.07.16.738731