Fred Rogers Namanda

FHOD3 and DIAPH3 control cell migration and differentially shift the balance of parallel and perpendicular stress fibers

This study identifies FHOD3 and DIAPH3 as regulators of stress fiber orientation and cell migration, showing they control distinct F-actin networks that influence cell shape and motility.

Leveraging Crosslinker Diffusion to Template Stiffness Gradients in Alginate Hydrogels

This paper develops a method to create stiffness gradients in alginate hydrogels using stencils, enabling the study of mechanosensitive cell behaviors like cancer cell invasion.

Formins and Arp2/3 Reciprocally Regulate Contact Guidance on Aligned Collagen Fibrils

This study investigates how formins and Arp2/3 regulate contact guidance on aligned collagen fibrils through cytoskeletal dynamics and myosin contractility.

Aligned collagen fibers drive distinct traction force signatures to regulate contact guidance

This study measures traction forces on aligned collagen fibers using d-TFM and finds that substrate stiffness and cytoskeletal regulators influence traction stress and migration.