BiophysicsThe Journal of General PhysiologyPeer-reviewed
Inhibition of CaV1.4 channels by CaV3 channel antagonists ML218 and Z944
Jinglang Sun, Juan de la Rosa Vázquez, Adriana Hernández González…·Amy Lee
This study investigates the effects of ML218 and Z944 on Cav1.4 channels, finding they inhibit Cav1.4 with lower IC50 values than Cav1.2 and highlight the role of methionine residues in ML218's mechanism.
DOI 10.1085/jgp.202513879