BiophysicsChemical SciencePeer-reviewed
Different molecular recognition by three domains of the full-length GRB2 to SOS1 proline-rich motifs and EGFR phosphorylated sites
Keita Tateno, Takami Ando, Maako Tabata…·Teppei Ikeya
This study uses NMR to show that GRB2's SH3 domains bind PRMs with different affinities and that phosphorylated EGFR binding affects GRB2's structure and domain interactions.
7 citations