Cancer BiologyEMBO Molecular MedicinePeer-reviewed
Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile
Audrey Burban, Cloé Tessier, Mathieu Larroquette…·Ahmad Sharanek
This study shows that mubritinib targets brain tumour stem cells by inhibiting complex I of the electron transport chain, delays glioblastoma tumourigenesis, and is safe in mice.
7 citations