Benjamin Dartigues

This study shows that mubritinib targets brain tumour stem cells by inhibiting complex I of the electron transport chain, delays glioblastoma tumourigenesis, and is safe in mice.

The paper benchmarks sequencing tools for identifying degraded proteins in ancient samples, finding optimal strategies for peptide and PTM detection.

DeepSpot enhances RNA spots in smFISH images using deep learning, enabling automated detection without manual parameter tuning and achieving over 97% accuracy.

DypFISH quantitatively investigates spatial and temporal subcellular localization of RNA and protein using micropatterning and fluorescence microscopy, revealing reproducible patterns and dynamics.