Author

Letal I. Salzberg

University College DublinORCID 0009-0007-6214-0008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Organism:fungi (other)· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Kenneth H. WolfeiD· 3 shared Padraic G. HeneghaniD· 3 shared Christina E. WeinbergiD· 1 shared Eoin Ó CinnéideiD· 1 shared Jan A. DewaldiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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3 shared papersEvolutionary Biology

Kenneth H. WolfeORCID

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3 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintOct 13, 2025

Zymocin-like killer plasmids were present in the common ancestor of terrestrial fungi

Padraic G. Heneghan, Letal I. Salzberg, Kenneth H. Wolfe

The paper identifies VLEs in two fungal phyla, suggesting they were present in the common ancestor of terrestrial fungi around 650 Mya.

DOI 10.1101/2025.10.13.682091

fungi (other)DNA methylation

𝕏 PostBluesky

Evolutionary BiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 10, 2025

Ancient origin and high diversity of zymocin-like killer toxins in the budding yeast subphylum

Padraic G. Heneghan, Letal I. Salzberg, Eoin Ó Cinnéide…·Kenneth H. Wolfe

The paper identifies 45 new zymocin-like toxin genes in budding yeasts, showing their diversity and suggesting VLEs have been parasitic for over 300 million years.

10 citations

yeastDNA methylation

𝕏 PostBluesky

Evolutionary BiologyFungal Genetics and BiologyPeer-reviewedJan 4, 2025

Zymocin-like killer toxin gene clusters in the nuclear genomes of filamentous fungi

Padraic G. Heneghan, Letal I. Salzberg, Kenneth H. Wolfe

The paper identifies zymocin-like toxin gene clusters in filamentous fungi, showing their evolutionary origin and horizontal transfer in mushrooms.

4 citations

fungi (other)statistical model

𝕏 PostBluesky