Author

Nicola Frericks

Ruhr University BochumORCID 0009-0007-6493-8187Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Csaba MiskeyiD· 2 shared Eike SteinmanniD· 2 shared Maike HerrmanniD· 2 shared Yannick BrüggemanniD· 2 shared André GömeriD· 1 shared Bevan SawatskyiD· 1 shared Bingqian QuiD· 1 shared Birthe M. Reinecke· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Csaba MiskeyORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 21, 2026

Yellow fever vaccine propagation in primary human hepatocytes triggers antiviral and cytolytic responses

Robin D. V. Kleinert, Maike Herrmann, André Gömer…·Richard J. P. Brown

This study compares antiviral and cytolytic responses in primary human hepatocytes to YFV vaccine and virulent strains, finding similar propagation kinetics but distinct transcriptional responses.

DOI 10.64898/2026.01.21.700765

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 22, 2023

Hepatitis C virus cell culture adaptive mutations enhance cell culture propagation by multiple mechanisms but boost antiviral responses in primary human hepatocytes

Nicola Frericks, Richard J.P. Brown, Birthe M. Reinecke…·Julie Sheldon

This study identifies cell culture adaptive mutations in HCV that enhance replicative fitness in cell lines but reduce virion production in primary human hepatocytes by boosting antiviral responses.

DOI 10.1101/2023.11.22.568224

humanbulk RNA-seq

𝕏 PostBluesky