Author

José Ortega

OptiScan (United States)ORCID 0009-0007-7115-2537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

Alec Basil HeckertiD· 1 shared Alonso CastroiD· 1 shared Alyssa Jimenez· 1 shared Anthony S. EritanoiD· 1 shared Arnold Tao· 1 shared Blake RiggsiD· 1 shared Catharine Lugar· 1 shared Charlene Bashore· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alec Basil HeckertORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJul 18, 2024

WRN Inhibition Leads to its Chromatin-Associated Degradation Via the PIAS4-RNF4-p97/VCP Axis

Fernando Rodríguez-Pérez, Dean E. Natwick, Lauren Schiff…·Stephen E. Basham

This study identifies a novel regulatory mechanism for WRN degradation via the PIAS4-RNF4-p97/VCP axis in MSI-H cancer cells using single molecule tracking and inhibitor screening.

22 citations

humanexperimental assay

𝕏 PostBluesky

GeneticsG3 Genes Genomes GeneticsPeer-reviewedMar 18, 2023

A deficiency screen of the 3rd chromosome for dominant modifiers of the Drosophila ER integral membrane protein, Jagunal

Gerson Ascencio, Matthew A. de Cruz, Judy Abuel…·Blake Riggs

The paper identifies suppressors and enhancers of the Jagn RNAi-induced rough eye phenotype in Drosophila through a deficiency screen on the 3rd chromosome.

1 citation

Drosophilaexperimental assay

𝕏 PostBluesky