Kristin Gennermann

The paper identifies tumor-reactive TCRs using T/N ratios and validates them with single-cell and spatial data, showing their tumor association and effector phenotype.

This paper introduces a TCR-V(D)J-sequence clustering method to identify tumor-specific common TCRs across cancers, showing their pan-cancer reactivity and potential for therapeutic applications.

The paper identifies T-cell receptors targeting KRAS Q61H neoantigen in NSCLC patients using antigen-agnostic screening and demonstrates their reactivity and potential for adoptive cell therapy.