Author

Volker Lennerz

Johannes Gutenberg University MainzORCID 0000-0002-9551-907XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:CITE-seq· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anja DrögeiD· 2 shared Dominik BentsiD· 2 shared Kristin GennermanniD· 2 shared Nadine GenzeliD· 2 shared Sigrid Schaper· 2 shared Steffen HennigiD· 2 shared Stephanie PlaßmanniD· 2 shared Volkhard SeitziD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Anja DrögeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tumor-versus-non-tumor T cell enrichment supported by single-cell and spatial phenotyping enables antigen-agnostic prioritization of candidate tumor-reactive TCRs

Volkhard Seitz, Jannik Franzen, Kristin Gennermann, Burkhard Hirsch, Sigrid Schaper, Anja Dröge, Mathias Dreger, Nadine Genzel, Stephanie Plaßmann, Dominik Bents, Jörn Glökler, Thomas Conrad, Christioph Loddenkemper, Karin Schmelz, Markus Morkel, , Sefer Elezkurtaj

The paper identifies tumor-reactive TCRs using T/N ratios and validates them with single-cell and spatial data, showing their tumor association and effector phenotype.

bioRxiv · Sep 24, 2026 · PreprintImmunology

T-cell receptors identified by a personalized antigen-agnostic screening approach target shared neoantigen KRAS Q61H

Volker Lennerz, Christoph Doppler, Martina Fatho, Anja Dröge, Sigrid Schaper, Kristin Gennermann, Nadine Genzel, Stephanie Plaßmann, David Weismann, Samuel W. Lukowski, Dominik Bents, Christina Beushausen, Karen Kriese, Hermann Herbst, Volkhard Seitz, , Steffen Hennig

The paper identifies T-cell receptors targeting KRAS Q61H neoantigen in NSCLC patients using antigen-agnostic screening and demonstrates their reactivity and potential for adoptive cell therapy.

Frontiers in Immunology · Mar 17, 2025Peer-reviewedImmunology