Cancer BiologyPLoS Computational BiologyPeer-reviewed
Ligand Discrimination in Immune Cells: Signal Processing Insights into Immune Dysfunction in ER+ Breast Cancer
Adina Matache, João Rodrigues Lima-Júnior, Maxim Borisovich Kuznetsov…·Russell C. Rockne
The paper measures ligand discrimination errors and molecular noise in immune cells of ER+ breast cancer patients compared to healthy controls using a communication model.
DOI 10.1371/journal.pcbi.1013615