Chenxuan Ji

CryoMV generates and validates continuous protein conformations from cryo-EM data using structure priors and real-particle validation, achieving high resolution and robustness on benchmark datasets.

CryoFlex quantifies structural motion between cryo-EM conformational states directly from density maps, achieving high accuracy and outperforming registration baselines.

CryoDDM improves cryo-EM reconstruction by denoising images to capture conformational heterogeneity, validated on proteasome, membrane protein, and spike protein datasets.