Xinsheng Wang

CryoMV: Structure-Prior-Guided Modeling and Real-Particle Validation of Continuous Conformational Transitions in Cryo-EM

CryoMV generates and validates continuous protein conformations from cryo-EM data using structure priors and real-particle validation, achieving high resolution and robustness on benchmark datasets.

CryoFlex characterizes structural motion between conformations directly from cryo-EM density maps

CryoFlex quantifies structural motion between cryo-EM conformational states directly from density maps, achieving high accuracy and outperforming registration baselines.

CryoDDM: CryoEM denoising diffusion model for heterogeneous conformational reconstruction

CryoDDM improves cryo-EM reconstruction by denoising images to capture conformational heterogeneity, validated on proteasome, membrane protein, and spike protein datasets.

MitoStructSeg: mitochondrial structural complexity resolution via adaptive learning for cross-sample morphometric profiling

MitoStructSeg accurately segments mitochondrial structures and quantifies morphological features in human and mouse tissues using a deep learning framework.