Molecular BiologybioRxivPreprint
Phenethylaminylation: Preliminary In Vitro Evidence for the Covalent Transamidation of Psychedelic Phenethylamines to Glial Proteins using 3,5-Dimethoxy-4-(2-Propynyloxy)-Phenethylamine as a Model Compound
Rajiv S. Rangan, R. Max Petty, Suchismita Acharya…·Abbot F. Clark
The paper investigates phenethylaminylation, a potential covalent modification of glial proteins by psychedelics, using a propargylated mescaline analog and click-chemistry in astrocyte cultures.
DOI 10.1101/2025.02.13.638188