Author

Kyle A. Emmitte

University of North TexasORCID 0000-0002-6643-3947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Abbot F. ClarkiD· 1 shared Alshaima’a M. QuniesiD· 1 shared Amy N. ShoreiD· 1 shared Brittany D. SpitznageliD· 1 shared C. David WeaveriD· 1 shared Calvin D. BrooksiD· 1 shared Chandra Lam· 1 shared David Peter SiderovskiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMolecular Biology

Abbot F. ClarkORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of Biological ChemistryPeer-reviewedAug 22, 2025

Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14

Percy S. Agogo-Mawuli, Isra Sadiya, Tigran M. Abramyan…·David Peter Siderovski

This paper identifies and validates non-covalent inhibitors of RGS14 GAP activity using structure-guided virtual screening and machine learning, showing improved potency and CNS penetration.

2 citations

protein structuredeep learning

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Molecular BiologybioRxivPreprintFeb 13, 2025

Phenethylaminylation: Preliminary In Vitro Evidence for the Covalent Transamidation of Psychedelic Phenethylamines to Glial Proteins using 3,5-Dimethoxy-4-(2-Propynyloxy)-Phenethylamine as a Model Compound

Rajiv S. Rangan, R. Max Petty, Suchismita Acharya…·Abbot F. Clark

The paper investigates phenethylaminylation, a potential covalent modification of glial proteins by psychedelics, using a propargylated mescaline analog and click-chemistry in astrocyte cultures.

DOI 10.1101/2025.02.13.638188

humanproteomics

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NeurosciencebioRxivPreprintOct 11, 2023

Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons

Amy N. Shore, Keyong Li, Mona Safari…·Matthew C. Weston

This study examines how a KCNT1 gain-of-function variant affects SST and PV GABAergic neurons, revealing differential functional outcomes and potential pathogenic mechanisms in DEEs.

7 citations

mouseelectronic health records

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