Author

Melvin Alappat

University of ZurichORCID 0009-0007-9392-6994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Sevasti GaspariiD· 2 shared Alexandre PicardiD· 1 shared Alice MastrangeloiD· 1 shared Anas MasoodiD· 1 shared Anja KipariD· 1 shared Bernard ThorensiD· 1 shared Charlie G. FoucheriD· 1 shared Dietmar BenkeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Sevasti GaspariORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 14, 2026

LightSuite: scalable atlas registration and cell detection across the central nervous system

Dimokratis Karamanlis, Yuqiao Xie, Charlie G. Foucher…·Sami El‐Boustani

LightSuite enables scalable, multimodal registration and cell detection across the central nervous system, improving precision and reproducibility in large animal studies.

DOI 10.64898/2026.10.13.757638

mousespatial transcriptomics

𝕏 PostBluesky

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedAug 20, 2026

Tmem117, an oligodendrocyte-enriched regulator of NCX activity, links myelin homeostasis to counterregulation and metabolic health.

Melvin Alappat, Marta Anna Mazurkiewicz, Iris Zambounis…·Sevasti Gaspari

This study identifies Tmem117 as an oligodendrocyte-enriched regulator of NCX activity, linking myelin homeostasis to counterregulatory response and metabolic health.

DOI 10.1073/pnas.2530122123

mouseexperimental assay

𝕏 PostBluesky