Min Zeng

This study demonstrates the transferability of homoserine lactone sensors between Bacillales bacteria, enabling programmable interphyla communication between Gram-negative and Gram-positive species.

The paper identifies highly specific LasR variants for HSL signals through mutagenesis and screening, improving signal discrimination in microbial consortia.

The paper develops synthetic HSL sensors in Bacillus subtilis using LuxR-type regulators and combinatorial promoters, achieving up to 293-fold activation and identifying sequence-function relationships.