Author

Jeffrey Boeren

Erasmus MCORCID 0009-0007-9717-0362Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:protein structure· 1

Frequent Co-Authors

Beatrice F. TaniD· 2 shared Cristina GontaniD· 2 shared Hegias Mira-BontenbaliD· 2 shared Jeroen DemmersiD· 2 shared Joost H. GribnauiD· 2 shared Sarra MerzoukiD· 2 shared Wilfred F. J. van IJckeniD· 2 shared Busra Goynuk· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Beatrice F. TanORCID

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2 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedSep 30, 2025

X-chromosome upregulation operates on a gene-by-gene basis at RNA and protein levels

Ryan Allsop, Jeffrey Boeren, Beatrice F. Tan…·Vincent Pasque

The paper shows that X-chromosome upregulation occurs gene-by-gene at both RNA and protein levels in mouse pluripotent stem cells.

4 citations

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintSep 18, 2025

HCFC1 and YY1 mediate recruitment of COMPASS and Integrator to initiate X chromosome inactivation.

Jeffrey Boeren, Beatrice F. Tan, Sarra Merzouk…·Joost H. Gribnau

This study identifies HCFC1 and YY1 as factors that recruit COMPASS and Integrator complexes to initiate X chromosome inactivation by regulating Xist and its cis-regulatory elements.

DOI 10.1101/2025.09.18.677040

𝕏 PostBluesky