Author

Lorenzo Tulli

University of BristolORCID 0009-0008-1268-1217Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Sofia F. OliveiraiD· 2 shared Adrian John MulhollandiD· 2 shared Alessio LodolaiD· 1 shared Allen E. HaddrelliD· 1 shared Andrew D. DavidsoniD· 1 shared Christiane SchaffitzeliD· 1 shared Fiona L. KearnsiD· 1 shared Imre BergeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

A. Sofia F. OliveiraORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 9, 2026

Cancer-associated mutations reconfigure dynamical responses in EGFR kinase

Lorenzo Tulli, Alessio Lodola, Adrian John Mulholland, A. Sofia F. Oliveira

This study uses D-NEMD simulations to show how cancer mutations in EGFR alter allosteric communication networks and signal propagation within the kinase domain.

DOI 10.64898/2026.10.08.757680

humanprotein structure

𝕏 PostBluesky

BiochemistrybioRxivPreprintNov 17, 2025

pH-induced structural changes in SARS-CoV-2 spike variants

A. Sofia F. Oliveira, Lorenzo Tulli, Fiona L. Kearns…·Adrian John Mulholland

This study uses D-NEMD simulations to show how pH changes induce variant-specific conformational changes in SARS-CoV-2 spike proteins, affecting their stability and entry mechanisms.

DOI 10.1101/2025.11.17.688702

virusprotein structure

𝕏 PostBluesky