Author

Zilan Qin

University of Hong KongORCID 0009-0008-1755-6802Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:software / tool· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Lei CheniD· 2 shared Minggao HeiD· 2 shared Ruibang LuoiD· 2 shared Xian YuiD· 2 shared Zhenxian ZhengiD· 2 shared X S GuoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersBioinformatics

Lei ChenORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 28, 2026

Client-server interfaces enable efficient agent-driven variant calling

Xian Yu, Zhenxian Zheng, Lei Chen…·Ruibang Luo

The paper re-architected a variant caller into a client-server system to improve agent-driven variant calling efficiency and reliability.

DOI 10.64898/2026.06.25.734665

whole-genome sequencingexperimental assay

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedJun 10, 2026

Leveraging ONT move table values for signal aware variant calling

Xian Yu, Zhenxian Zheng, Lei Chen…·Ruibang Luo

Clair3 v2 improves variant calling accuracy for Oxford Nanopore Technologies sequencing by using move table data and dwelling time, achieving higher F1-scores for SNPs and Indels.

2 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky