Author

Alok Apan Swatiputra

Howard Hughes Medical InstituteORCID 0009-0008-2015-0328Unclaimed ORCID profile · follow to get notified of new preprints

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Biochemistry· 1

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Approach:experimental assay· 1

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Filip BoškovićiD· 1 shared Jack W. SzostakiD· 1 shared Jian ZhangiD· 1 shared

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2026-2026 · peak 1/yr

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Filip BoškovićORCID

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BiochemistryJournal of the American Chemical SocietyPeer-reviewedMar 30, 2026

Influence of phosphate activation chemistry on the selection of the primordial genetic alphabet

Filip Bošković, Jian Zhang, Alok Apan Swatiputra, Jack W. Szostak

This study compares two phosphate-activation chemistries' effects on nucleotide modifications, showing that primordial nucleotides are more susceptible to modification, which may explain the selection of the canonical genetic alphabet.

2 citationstop 4%

experimental assay

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