Hamish Forrest

The paper uses long-read RNA-seq to study splicing changes in an Alzheimer's mouse model, identifying novel transcript isoforms and alternative splicing events in response to amyloid-beta.

This study shows that the FUSDelta14 mutation causes neurodevelopmental and systemic metabolic issues in mice, including brain structural abnormalities and metabolic pathway changes.

This study uses home-cage video tracking to analyze voluntary behaviors in mice, revealing complex phenotypes and sexual dimorphism in a Huntington's disease model.

The paper identifies a transcriptomic axis that predicts how cortical interneurons modulate activity across brain states.

This paper develops a standardized task for measuring decision-making in mice, showing reproducible results across multiple laboratories and providing a public dataset and tools.