Axel Fehrenbach

The paper analyzes CRISPR systems in prokaryotes, finding that multiple CRISPR arrays co-occur with Cas loci, vary in structure, and may function independently or collaboratively.

CRISPR-evOr predicts CRISPR array orientation by analyzing evolutionary patterns, improving accuracy for arrays other tools cannot confidently resolve.

SpacerPlacer reconstructs ancestral CRISPR array evolution, revealing frequent spacer deletions and a decrease in deletion frequency towards both ends of arrays.