Brian S.C. Constantinescu

The paper identifies brainstem circuits that transform dental sensory input into coordinated jaw opening by linking sensory afferents to specific motor pools.

This study identifies sensory fiber types in mouse TMJ tissues using immunohistochemistry, finding peptidergic fibers dominate with minimal non-peptidergic nociceptors.

This study identifies intradental high-threshold mechano-nociceptors that detect tooth damage, produce pain, and trigger protective reflexes.