Hongni Liu

This study identifies Xap5 as a master regulator of primary cilia formation by interacting with Nono to activate Sox5 and Sox9, revealing a conserved transcriptional network involved in ciliary diversity.

This study identifies XAP5 and XAP5L as antagonistic transcription factors that regulate ciliary gene expression during spermatogenesis, with XAP5 promoting and XAP5L inhibiting ciliary transcription factors at different stages.

This study identifies Edf1 as an essential transcription activator for multiciliogenesis, showing its role in ciliary gene expression and its impact on hydrocephalus in mice.

This study identifies nuclear cytoophidia as regulators of Impdh2 transcriptional activity, impacting skeletal development and homeostasis through effects on endochondral ossification and osteoclast function.