Systems BiologybioRxivPreprint
Stochasticity in Metabolism: Oxidative Stress Response Phenotypes As Emergent Consequences of Network Topology
Aleksandar Mihnev, Dana Luong, Jonah Porat, Roger Chang
The paper models oxidative stress response in E. coli using a genome-scale metabolic model to show that bimodal killing under H2O2 stress emerges from network topology and stochastic sampling.
DOI 10.64898/2026.10.23.761362