Author
University of WashingtonORCID 0009-0008-5802-7130Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Silvia Casadei, Matthew W. Snyder, Ivan M. H. Woo…·Lea M. Starita
The paper uses saturation genome editing to assess the functional impact of RAD51D and XRCC2 variants, showing high accuracy in distinguishing pathogenic from benign variants.
Malvika Tejura, Y P Chen, Abbye E. McEwen…·Lea M. Starita
The paper develops a scalable workflow to reclassify variants of uncertain significance using experimental and predictive evidence, resolving 75% of VUS in 40 genes.
Ivan M. H. Woo, Silvia Casadei, Matthew W. Snyder…·Lea M. Starita
The paper uses saturation genome editing to evaluate BARD1 variants, resolving most variants of uncertain significance and confirming their role in tumor suppression.