Author
University of Massachusetts Chan Medical SchoolORCID 0009-0008-7222-3381Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Hassan H. Fakih, Ashley Summers, Qi Tang…·Anastasia Khvorova
This paper introduces fully modified RNA nanostructures (FMRNs) for multi-gene silencing beyond the liver, showing enhanced pharmacokinetics, extrahepatic delivery, and programmable control over siRNA stoichiometry.
Hassan H. Fakih, Masahiro Ohara, Ashley Summers…·Jonathan K. Watts
This study develops D-siRNA, an albumin-binding dendrimer-conjugated siRNA, showing effective and durable gene silencing in the CNS with no detectable toxicity.
Hassan H. Fakih, Clemens Lochmann, Rosemary Gagnon…·Anastasia Khvorova
This study develops chemically defined siRNAs for durable gene modulation in muscle and heart, showing long-term silencing and functional benefits with minimal toxicity.