Author

Lyazat Kurenbekova

Baylor College of MedicineORCID 0009-0008-7297-0344Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Bikesh Kumar NiralaiD· 1 shared Jason Todd YusteiniD· 1 shared Ryan Lane Shuck· 1 shared Sarah S. Kappa· 1 shared Tajhal Patel· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Bikesh Kumar NiralaORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 26, 2026

MYC-Hyperactivated Osteosarcoma Models Exhibit Resistance to Cabozantinib plus TIGIT Blockade

Sarah S. Kappa, Tajhal Patel, Bikesh Kumar Nirala…·Jason Todd Yustein

This study evaluates the efficacy of cabozantinib plus TIGIT blockade in osteosarcoma models, finding improved outcomes in p53-driven tumors but resistance in MYC-hyperactivated models due to myeloid recruitment and ECM remodeling.

DOI 10.64898/2026.09.21.753033

mousebulk RNA-seq

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